The bulb ulcer stenosis, becoming exceptional in developed countries, remains frequent in our\ncountry despite the use of the antisecretory. The purpose of our study was to study epidemiological,\ndiagnostic, and evolutionary complication particularities, and to find potential predictive factors\nof resistance of ulcer stenosis of the bulb to the pump inhibitors Proton through a recent series.\nThis is a retrospective and descriptive study involving 105 patients, treated for ulcer stenosis of\nthe bulb between January 2007 and December 2012. All our patients had received inhibitors of\nProton pump, parenterally for 7 days. They were divided into 2 groups according to their response\nto treatment: the first group (G1) was sensitive and the second (G2) was resistant. All patients of\nthe G2 were operated. We had compared the two groups. There was no statistically significant difference\nconcerning age, sex, blood group and smoking between the two groups. In univariate\nstudy, the age of the epigastralgies was greater than or equal to 9 years; the clapotage fasting, dilation\nand gastric atony, objectified by the oesogastroduodenal transit were significantly associated\nwith the failure of medical treatment. Only gastric atony and seniority of the disease over 9\nyears were independent risk factors of resistance to the Proton pump inhibitors in multivariate\nstudy.
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